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TNFα and IFNγ expression in CD4+CD45RO+ T-cells by intracellular flow cytometry after Spike peptide stimulation in CVID patients and HD (A), and in CVID patients grouped by their antibody response following third BNT162b2 mRNA COVID-19 vaccination (B). Levels of significance by Two-tailed Mann–Whitney U-test: **** p < 0.0001, *** p < 0.001, * p < 0.05.
