Table 1.
Genes significantly (adjusted p value < 0.05) modified by the treatment of βlox5 with L. johnsonii-derived NVs or cell membrane isolates when compared to vehicle control.
| NV10 vs CTRL | MEMB5 vs CTRL | ||||
|---|---|---|---|---|---|
| Gene name | Fold change(log2) | Adjusted p value | Gene name | Fold change(log2) | Adjusted p value |
| CYP1B1 | 2.3 | 3.37E-12 | CYP1B1 | 2.3 | 3.27E-05 |
| VIPR1 | 1.7 | 5.71E-11 | TXNIP | 1.2 | 0.00337 |
| MX1 | 2.4 | 7.84E-06 | |||
| MX2 | 2.8 | 9.37E-06 | |||
| IFI44L | 3.3 | 3.02E-05 | |||
| CYP1A1 | 3.6 | 0.000338 | |||
| TIPARP | 1.2 | 0.000403 | |||
| CDK15 | 1.6 | 0.000979 | |||
| DDX60 | 1.0 | 0.001631 | |||
| EPSTI1 | 1.5 | 0.001781 | |||
| STC2 | 1.1 | 0.00224 | |||
| OAS2 | 3.0 | 0.00224 | |||
| IFI44 | 1.3 | 0.003432 | |||
| SECTM1 | 1.3 | 0.007822 | |||
| AHRR | 1.2 | 0.007904 | |||
| IL1B | 1.1 | 0.011816 | |||
| OASL | 1.5 | 0.012745 | |||
| IFIT1 | 1.3 | 0.024639 | |||
| ALDH1A3 | 0.9 | 0.024639 | |||
| OAS1 | 2.1 | 0.037023 | |||
| IL6 | 1.3 | 0.039443 | |||