Table 3.
Comparison of the diagnostic accuracies of acute/paired MAT (final MAT) with IgM dot ELISA dipstick test and latex agglutination test by considering MAT as reference/gold standard as well as imperfect test as in BLCM.
| Parameters | MAT Considered as Gold Standard Test (%) | Bayesian Latent Class Model (%) |
|---|---|---|
| Prevalence | 19.4 (15.4–24.1) | 18.9 (14.9–23.2) |
| Acute MAT/Paired MAT | ||
| Sensitivity | 100 | 98.2 (93.0–99.8) |
| Specificity | 100 | 98.9 (97.2–99.7) |
| PPV | 100 | 95.2 (88.4–98.8) |
| NPV | 100 | 99.6 (98.3–100) |
| rLigA/BCon1-5-based LAT | ||
| Sensitivity | 90.9 (80.6–96.3) | 94.9 (87.8–98.6) |
| Specificity | 99.6 (97.7–100) | 99.9 (99.1–100) |
| PPV | 98.4 (90.0–99.9) | 99.6 (95.9–100) |
| NPV | 97.8 (95.1–99.1) | 98.8 (97.1–99.7) |
| rLigA/BCon1-5-based IgM Dot ELISA Dipstick Test | ||
| Sensitivity | 95.5 (86.4–98.8) | 99.6 (96.0–100) |
| Specificity | 99.6 (97.7–100) | 99.9 (99.1–100) |
| PPV | 98.4 (90.5–99.9) | 99.6 (96.2–100) |
| NPV | 98.9 (96.6–99.7) | 99.9 (99.1–100) |