Table A1.
Case series where ultrasonography of uterine lesions was supplemented by core needle biopsy. Clinical, sonological and histological data are provided, together with clinical significance of addition of core needle biopsy to ultrasonography.
| Case Number (Age, Years Old) |
Ultrasound Diagnosis of Uterine Lesion |
Figure | Initial Treatment/ Histological Diagnosis Required (Doctor’s Decision) |
Initial Patient’s Willingness to Undergo Surgery for the Uterine Lesion |
Histology from Core Needle Biopsy | Patient Decision to Undergo Surgery for the Uterine Lesion |
Histology from Definitive Surgery | Did Core Needle Biopsy Provided Additional Information to Ultrasound |
Did Core Needle Biopsy Provided Useful Information for the Clinical Management |
|---|---|---|---|---|---|---|---|---|---|
| 1 (44) | Typical uterine lesion (myoma) | Figure A1 | No | Yes | Leiomyoma, cellular variant (UG-TUC core needle biopsy) | Yes (lesion enlarged during follow-up) |
Leiomyoma, cellular variant | No | Yes |
| 2 (36) | Sarcoma suspicion | Figure A2 | Yes | Tumorectomy, uterus preservation (young age) | LMS (UG-TUC core needle biopsy) |
Yes | LMS | No | Yes |
| 3 (37) | Atypical uterine lesion | Figure A3 | Yes | No | Lipoleiomyoma (UG-TUC core needle biopsy) |
No | - | Yes | Yes |
| 4 (56) | Atypical uterine lesion | Figure A4 | Yes | Yes | Leiomyoma (transvaginal ultrasound guided core needle biopsy) |
Yes | Leiomyoma and adenomyosis | Yes | No |
| 5 (50) | Atypical uterine lesion (metastatic adenocarcinoma G3 in inguinal lymph node) |
Figure A5 | Yes | No | Leiomyoma (UG-TUC core needle biopsy) |
No | Uterus / tumor not resected because primary urological carcinoma was diagnosed |
Yes | Yes |
| 6 (38) | Atypical uterine lesion | Figure A6 | Yes | No | Leiomyoma, epithelioid variant (UG-TUC core needle biopsy) |
Yes (lesion enlarged during follow-up) | Leiomyoma, epithelioid variant | Yes | Yes |
| 7 (29) | Atypical uterine lesion | Figure A7 | Yes | Yes | Leiomyoma (UG-TUC core needle biopsy) |
Yes | Leiomyoma with signs of degenerations |
Yes | Yes |
| 8 (52) | Atypical uterine lesion | Figure A8 | Yes | Yes | Total abdominal hysterectomy performed without core need biopsy, because of patients age and lesion ultrasound pattern recognition. Note: frozen section result: leiomyoma |
Yes | STUMP | - | - |
LMS, leiomyosarcoma; STUMP, smooth muscle tumor of uncertain malignant potential; UG-TUC, ultrasound-guided transuterine cavity; Note. There were no complications concerned with UG-TUC core needle biopsy procedure.