TABLE 2.

Intradomain nucleotide signature features for the Archaea 16S rRNA sequences (54, 56)

Position(s)b	Intradomain nucleotide signature feature fora:
	Eury	Cren	MBG B	pMC2A36	VC2.1Arc31	MBG D	pMC2A33	VC2.1Arc6
27:556	G:C	C:G	Cren	Cren	U:G	Eury	Eury	Eury
28:555	G:Y	C:G	Cren	Cren	Cren	Eury	Eury	Eury
30:553	Y:R	G:C	Cren	Cren	Cren	Eury	Eury	Eury
34:550	U:G	C:G	ND:G	Eury	Eury	Eury	Eury	Eury
289:311	C:G	G:C	A:U (APA3-11)	A:U	A:U	Eury	Eury	Eury
			Cren (CRA8-27)
501:544	R:Y	C:G	Eury	Eury	Eury	Eury	U:A	Eury
503:542	C:G	G:C	Cren	Cren	Cren	Eury	Eury	Eury
504:541	Y:R	G:Y	A:U	A:U	A:U	Eury	Eury	Eury
513:538	C:G	U:A	Cren	Cren	Cren	G:U	G:U	Eury
518	C	U	Eury	Eury	Eury	Eury	Eury	Eury
658:747	Y:R	G:C	Cren	Cren	Cren	Eury	Eury	Eury
692	U	C	Eury	Eury	Eury	Eury	Eury	Eury
965	Y	G	Eury	Eury	Eury	Eury	Eury	Eury
1074:1083	A:C	G:U	Cren	Cren	Cren	Eury	Eury	Eury
1244:1293	Y:R	R:Y	Cren	Cren	Cren	Eury (U:A)	Eury	Eury
1252	U	C	Eury	Eury	Eury	Eury	Eury	A
1335	C	G	Cren	Cren	U	Eury	Eury	Cren
1408	A	G	Cren	Cren	Cren	Eury	Eury	Eury

^aCrenarchaeota (Cren) and Euryarchaeota (Eury) signature sequences where R = purine and Y = pyrimidine. MBG, marine benthic group. 

^bNumbering follows that for the E. coli 16S rRNA sequence.