Table 3.
Postoperative anemia of TKA: univariate and multivariate analysis of possible risk factors in the validation cohort.
| Variables | Univariate analysis | p-value | Multivariate analysis | p-value |
|---|---|---|---|---|
| OR (95% CI) | Adjusted OR (95% CI) | |||
| Age (years) | ||||
| <60 | 1.000 | |||
| 60–65 | 0.764 (0.385–1.520) | 0.443 | ||
| 65–70 | 0.836 (0.439–1.589) | 0.584 | ||
| 70–75 | 0.709 (0.350–1.437) | 0.340 | ||
| >75 | 0.638 (0.310–1.313) | 0.222 | ||
| Sex | ||||
| Female | 1.000 | 1.000 | ||
| Male | 0.306 (0.138–0.678) | 0.004 | 0.399 (0.177–0.900) | 0.027 |
| Drug | ||||
| No | 1.000 | |||
| Yes | 0.846 (0.451–1.588) | 0.603 | ||
| BMI (kg/m2) | ||||
| <24 | 1.000 | |||
| 24–28 | 0.747 (0.440–1.266) | 0.278 | ||
| >28 | 0.908 (0.534–1.544) | 0.721 | ||
| Infusion of protein | ||||
| No | 1.000 | |||
| Yes | 0.697 (0.424–1.145) | 0.154 | ||
| Abnormally high CRP levels | ||||
| No | 1.000 | |||
| Yes | 1.211 (0.682–2.152) | 0.514 | ||
| Hb < 12.0 g/dL (male) or <11.0 g/dL (female) (preoperative anemia or not) | ||||
| No | 1.000 | 1.000 | ||
| Yes | 6.214 (2.937–13.15) | <0.001 | 6.152 (2.724–13.89) | <0.001 |
| Abnormally high ESR levels | ||||
| No | 1.000 | 1.000 | ||
| Yes | 2.160 (1.403–3.326) | 0.000 | 1.666 (1.043–2.66) | 0.033 |
| Sides of TKA | ||||
| One side | 1.000 | |||
| Two sides | 2.63 (1.737–3.981) | <0.001 | 2.90 (1.866–4.495) | <0.001 |
| Number of comorbidities | ||||
| <2 kinds of comorbidities | 1.000 | |||
| 2 kinds of comorbidities | 0.946 (0.570–1.571) | 0.830 | ||
| >2 kinds of comorbidities | 1.154 (0.710–1.875) | 0.562 | ||