Table 3.
In vitro antioxidant and anti-glycation effects of rooibos, hibiscus, yerba mate extracts.
| Assay | Species [Extract] |
Measure | Dose or EC50 | Reference |
| Antioxidant |
H. sabdariffa [Ethanolic] |
Lipid peroxidation (SH-SY5Y cells) |
Control: 800% Extract (100 µg/mL): 300% |
[141] |
| ROS production (SH-SY5Y cells) |
Control: 130% Extract (100 µg/mL): 100% |
|||
|
H. sabdariffa [Methanolic] |
Malondialdehyde | EC50 22 μg/mL | [144] | |
| Monoamine Oxidase | EC50 44 μg/mL | |||
| ATPase activity | EC50 22 μg/mL | |||
| Anti-glycoxidation |
A. linearis [Aqueous] |
AGE formation inhibition (Fluorescence 340/420 nm) Glucose in BSA system |
Control (aminoguanidine): 45% Green extract (200 μg/mL): 45% Fermented extract (200 μg/mL): 55% |
[145] |
|
H. rosa-sinensis [Aqueous] |
AGE formation inhibition (Fluorescence 340/420 nm) Fructose in BSA system |
Control (Aminoguanidine): IC50 6 μg/mL Extract: IC50 67 μg/mL |
[146] | |
|
I. paraguariensis [Aqueous] |
AGE formation inhibition (Fluorescence 340/420 nm) Fructose in BSA system |
Control (Fructose): 4000 a.u. Extract (2.5 µg/mL): 3000 a.u. |
[147] | |
| AGE formation inhibition (Fluorescence 340/420 nm) Methylglyoxal in BSA system |
Control (green tea): 65 a.u. Extract (20 µg/mL): 42 a.u. |
[20] |
BSA: bovine serum albumin.