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. 2022 Jun 7;11(12):1676. doi: 10.3390/foods11121676

Table 3.

In vitro antioxidant and anti-glycation effects of rooibos, hibiscus, yerba mate extracts.

Assay Species
[Extract]
Measure Dose or EC50 Reference
Antioxidant H. sabdariffa
[Ethanolic]
Lipid peroxidation
(SH-SY5Y cells)
Control: 800%
Extract (100 µg/mL): 300%
[141]
ROS production
(SH-SY5Y cells)
Control: 130%
Extract (100 µg/mL): 100%
H. sabdariffa
[Methanolic]
Malondialdehyde EC50 22 μg/mL [144]
Monoamine Oxidase EC50 44 μg/mL
ATPase activity EC50 22 μg/mL
Anti-glycoxidation A. linearis
[Aqueous]
AGE formation inhibition
(Fluorescence 340/420 nm)
Glucose in BSA system
Control (aminoguanidine): 45%
Green extract (200 μg/mL): 45%
Fermented extract (200 μg/mL): 55%
[145]
H. rosa-sinensis
[Aqueous]
AGE formation inhibition
(Fluorescence 340/420 nm)
Fructose in BSA system
Control (Aminoguanidine): IC50 6 μg/mL
Extract: IC50 67 μg/mL
[146]
I. paraguariensis
[Aqueous]
AGE formation inhibition
(Fluorescence 340/420 nm)
Fructose in BSA system
Control (Fructose): 4000 a.u.
Extract (2.5 µg/mL): 3000 a.u.
[147]
AGE formation inhibition
(Fluorescence 340/420 nm)
Methylglyoxal in BSA system
Control (green tea): 65 a.u.
Extract (20 µg/mL): 42 a.u.
[20]

BSA: bovine serum albumin.