TABLE 3.
Cytotoxicities of betulinic acid and compounds 2 to 5
| Compound | ED50s for human melanoma cell lines (μg/ml)
|
|
|---|---|---|
| Mel-1 | Mel-2 | |
| Betulinic acid | 3.3 | 1.0 |
| 2 | 16.0 | 0.1 |
| 3 | >20 | 0.2 |
| 4 | >20 | 0.3 |
| 5 | >20 | >20 |
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