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. 2022 Jun 20;13(6):1101. doi: 10.3390/genes13061101
ATM Ataxia telangiectasia mutated
alt-NHEJ Alternative non-homologous end joining
B-NHEJ Backup nonhomologous end-joining
BER Base excision repair
51BP1 P51 binging protein 1
c-NHEJ Canonical non-homologous end joining
CtIP BRCA1 C-terminal Interacting Protein
D-NHEJ DNA-PK-mediated nonhomologous end-joining
DDR DNA damage response
DSB DNA double strand break
ESCC Esophageal squamous cell carcinoma
FDA Food and drug administration
HR Homologous recombination
MMEJ Microhomology-mediated end-joining
NHEJ Nonhomologous end-joining
PARPi Poly (ADP-ribose) polymerase 1 inhibitor
Polθ Polymerase theta
Polθi Polymerase theta inhibitor
ROS Reactive oxygen species
RBBP8 Retinoblastoma binding protein 8
RPA Replication protein A
RIF1 Replication timing regulatory factor 1
SSA Single strand annealing
SSB Single strand break
ssDNA Single stranded DNA
SL Synthetic lethality
XPF Xeroderma pigmentosum complementation group F