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. 2022 Jun 8;23(12):6418. doi: 10.3390/ijms23126418

Figure 7.

Figure 7

Auranofin inhibits SARS-CoV-2 proliferation in living organisms. Huh7 infection is associated with SARS-CoV-2 for 2 h at a multitude of infected (MOI) from one before ever being incubated with 4 M auranofin or 0.1 DMSO. Cell lysates and culturing filtrates were obtained 24 and 48 h after transmission, and viral RNA rates were measured using RT-PCR using primers and probe targeting the SARS-CoV-2 N1 and SARS-CoV-2 N2 regions. After measuring, standardizing, and correcting the human RNA extracted form tumor cells, the viral RNA values per ug of total cellular RNA were determined. The outcomes were compared for all specific primers, revealing a significant drop in viral RNA following 24 and 48 h. SARS-CoV-2 transmissibility titers were obtained using a cell test.48 h after invasion, in culturing filtrates The data are the mean SEM of two separate tests performed in duplicate, t-test ** p < 0.001. Reprinted/adapted with permission from Ref. [134].