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. 2022 Jun 8;23(12):6418. doi: 10.3390/ijms23126418

Table 6.

Toxicity of HL, metal salts, and newly created complexes on Daphnia magna.

Compound Incubation Period
1 d 2 d d1 2 d 1 d 2 d
LC50 (µM) Goodness of Fit (r2) CI 95% of LC50 (µM)
HL 53.09 52.60 0.9918 0.9849 ND* ND*
(Cu(L)(CH3COO)).2H2O 69.59 13.09 0.9021 0.9389 44.11–109.8 8.89–19.26
(Cu(L)(NO3)).H2O 316.90 5.61 0.7842 0.8742 2.19–2.81 0.51–0.98
(Cu(L)(ClO4)).H2O ND* ND* ND* ND* ND** ND*
(Cu(L)(Cl)).2H2O 393.8 69.53 0.9966 0.8159 374.4–414.2 33.96–142.4
(Co(L)2) 278.2 2.38 0.8655 0.9145 166.4–465.4 158.4–265.8
(Zn(L)2) 33.91 0.84 0.9452 0.7553 23.27–49.4 0.33–2.12
(Ni(L)(Cl)) 350.8 209.7 0.9935 0.9315 320.6–383.8 149.6–294.1
(Pt(L)(Cl)) 468.60 78.19 0.9490 0.9546 400.6–548.3 57.44–106.5
Cu(CH3COO)2 9.86 0.44 0.9980 ND* ND** ND**
CuCl2 4.23 0.97 0.9890 0.9302 3.709–4.815 ND**
Cu(NO3)2 7.43 1.39 0.9586 0.9446 6.04–915 1.08–1.78
Cu(ClO4)2 0.39 0.31 0.9777 0.9794 2.34–3.76 0.99–1.22
CoCl2 205.20 31.37 0.9717 0.876 158.4–265.8 17.06–57.7
ZnCl2 15.39 0.89 0.9190 0.9691 9.42–25.15 0.79–1.02
NiCl2 100 16.25 0.9827 0.9624 98.31–101.7 11.86–22.27
K2PtCl4 27.70 5.63 0.9918 0.9364 21.86–35.11 3.953–8.012

ND*—not detected since the largest L% is 10% following 1 d and 35% following 2 d, respectively; ND**—not detected because of CI 95% is really wide.