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. 2022 Jun 7;23(12):6387. doi: 10.3390/ijms23126387

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Box plots for metabolites and metabolite families involved in lipid metabolism and structure in the aortic block. Interquartile range has been colored green, blue, and red for the SHAM, HCD, and ANG groups respectively. Mann–Whitney–Wilcoxon testing was used for comparing group medians pairwise. Legend: total carnitine content: sum of free carnitine (C0) and all acylcarnitine species; C2: acetylcarnitine; hexose: sum of all L-hexoses, mainly D-glucose; PC: sum of all phosphatidylcholine species; Lyso PC (unsaurated/saturated): sum of all lysophosphatidylcholine species with an unsaturated acyl moiety divided by the sum of all lysophosphatidylcholine species with a saturated acyl moiety; SM: sum of all sphingomyelin species; *: p ≤ 0.05; **: p ≤ 0.01.