Table 1.

Summary of microRNAs differentially expressed in patients with primary intracerebral hemorrhage respect to healthy controls, in more than two independent studies. Papers that lacked quantitative analysis were excluded. Based on the systematic review performed by Fullerton and co-workers [67].

ICH Phenotype Studied (n)	MiRNA	Upregulated or Downregulated	Study Population/Ancestry [Ref]
HE in patients with ICH (n = 30) vs. Non-HE in ICH patients (n = 49) HE-ICH vs. healthy controls (n = 30)	miRNA-29c miRNA-29c	Upregulated	China [72]
Hematoma volume (n = 33) vs. healthy controls (n = 18) Perihematomal edema	miRNA-126 miRNA-146a miRNA-let-7a miRNA-26a miRNA-126	Downregulated	China [73]
ICH patients (n = 30) vs. control (n = 30) Perihematomal edema	miRNA-23a-3p miRNA-130a miRNA-26a miRNA-146a miRNA- 23a-3p	Upregulated Downregulated Upregulated	China [74]
ICH patients (n = 80) vs. healthy control (n = 30)	miRNA-155	Upregulated	China [75]
ICH patients (n = 106) vs. healthy control (n = 50)	miRNA-145 miRNA-223, and miRNA-155 miRNA-181b	Upregulated Downregulated	China [76]

Abbreviations: ICH = intracerebral hemorrhage; MiRNA = micro RNA; HE = hematoma enlargement; vs. = versus.