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. 2022 Jun 17;23(12):6749. doi: 10.3390/ijms23126749

Figure 2.

Figure 2

HBP congenic background increases male Lox+/C285F aortic dilation rate. (A,B), HBP background increases SBP in Lox+/+ and Lox+/C285F mice ((A), Lox effect p < 0.05, HBP effect p < 0.0001, two-way ANOVA, followed by Sidak multiple testing with p values shown in the graph) and produces larger diameter vessels in Lox+/C285F males by 3 months of age ((B), *—C57 Lox+/C285F vs. HBP Lox+/C285F, ^—C57 Lox+/+ vs. HBP Lox+/C285F, and #—HBP Lox+/+ vs. HBP Lox+/C285F, two-way ANOVA). C57 Lox+/+ and C57 Lox+/C285F mice are those used in Figure 1. For all tests *, ^, # p < 0.05, ^^, ## p < 0.01, ***, ### p < 0.001, and **** p < 0.0001.