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Schematic presentation of calreticulin (CRT) and location of C-terminal frameshift substitutions. The different regions are coloured according to Boelt et al. [13], and the C-terminal part from residue 361 of native CRT, CRTfs L367, and CRTfs K385 are highlighted (bottom). Acidic residues are coloured blue while basic residues are coloured red. The KDEL sequence of native CRT is underlined.
