Table 3.

SSI-HYB reactivity to functionality-substituted peptides. The amino acids in brackets represent the substitution introduced. The peptide CREAALQGWTEA was used for generation of substituted peptides. ++ represents reactivity similar to the control, + represents medium reactivity, − represents no reactivity.

	[C→M]1	[A→G]4	[L→I]6	[W→F]9	[T→S]10	[E→D]11	[A→G]12
SSI-HYB 385-01	−	++	++	++	+	−	++
SSI-HYB 385-02	−	++	++	−	++	++	++
SSI-HYB 385-03	−	++	++	++	++	++	++
SSI-HYB 385-04	−	++	++	−	++	++	++
SSI-HYB 385-06	++	++	++	++	++	++	++
SSI-HYB 385-07	−	+	+	++	++	−	++
SSI-HYB 385-08	−	+	++	++	++	−	++
SSI-HYB 385-09	−	++	++	++	++	−	++