Table 1.
Two-way ANOVA or mixed model results. Significant findings are bolded.
| Attribute | Task Group | Treatment Group | Interaction |
|---|---|---|---|
| Metaphyseal Trabeculae, MicroCT (2-way ANOVA) | |||
| % BV/TV | p = 0.0001 | p = 0.04 | p = 0.0004 |
| Tb.N | p < 0.0001 | p = 0.004 | p < 0.0001 |
| Tb.Sp | p = 0.003 | p = 0.91 | p = 0.005 |
| Tb.Th | p < 0.0001 | p = 0.42 | p = 0.32 |
| BS/BV | p = 0.0004 | p = 0.27 | p = 0.59 |
| DA | p = 0.006 | p = 0.001 | p = 0.191 |
| BMD | p < 0.0001 | p = 0.04 | p = 0.12 |
| Metaphyseal Trabeculae, Histomorphometry (2-way ANOVA) | |||
| N.Ob/BS | p = 0.002 | p = 0.14 | p = 0.03 |
| % OV/BV | p = 0.008 | p = 0.006 | p = 0.02 |
| % OS/BS | p = 0.02 | p = 0.14 | p = 0.02 |
| O.Wi | p = 0.36 | p = 0.002 | p = 0.55 |
| N.Oc/BS | p < 0.0001 | p < 0.0001 | p < 0.0001 |
| % Oc/BS | p = 0.005 | p = 0.03 | p = 0.03 |
| Mid-diaphyseal cortical bone, MicroCT (2-way ANOVA) | |||
| Tr.Ar | p = 0.03 | p = 0.09 | p = 0.14 |
| Ct.Ar | p < 0.0001 | p = 0.31 | p = 0.45 |
| Ct.Ar/Tr.Ar, % | p < 0.0001 | p = 0.83 | p = 0.85 |
| Ct.Th | p < 0.0001 | p = 0.93 | p = 0.38 |
| Ma.Ar | p < 0.0001 | p = 0.71 | p = 0.056 |
| Ps.Pm | p = 0.04 | p = 0.10 | p = 0.04 |
| TMD | p < 0.0001 | p = 0.94 | p = 0.32 |
| Serum Biomarkers (2-way ANOVA) | |||
| Osteocalcin | p = 0.81 | p = 0.08 | p = 0.0003 |
| CTX-1 | p = 0.06 | p = 0.31 | p = 0.0005 |
| TNF-α | p = 0.12 | p = 0.27 | p = 0.04 |
| Flexor Digitorum Muscle (2-way ANOVA) | |||
| # CD68+ cells | p < 0.0001 | p < 0.0001 | p < 0.0001 |
| CSA (whole muscle) | p < 0.0001 | p = 0.57 | p = 0.44 |
| Attribute | Time | Treatment | Interaction |
| Voluntary Reach Outcomes (Mixed Model) | |||
| Reach Rate | p = 0.28 | p = 0.04 | p = 0.01 |
| Pulling Force | p = 0.34 | p = 0.01 | p = 0.49 |
| Grasp Duration | p = 0.047 | p = 0.04 | p = 0.03 |
Abbreviations as indicated in the text of the results.