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. 2022 Jun 16;19(12):7417. doi: 10.3390/ijerph19127417

Table 2.

Trends in personal payments from Japanese pharmaceutical companies to infectious disease specialists certified by the Japanese Association for Infectious Disease between 2016 and 2019.

Variables 2016 2017 2018 2019 Average Yearly Change (95%CI), % p-Value Combined Total
All pharmaceutical companies
Total payments, $ 4,662,217 4,215,566 4,538,520 4,367,767 17,78,4070
Average payments (SD), $ 6134 (15,283) 5775 (13,410) 6108 (13,324) 6033 (11,837) −1.2 (−4.7–2.3) 0.49 16,857 (45,010)
Median payments (IQR), $ 1604 (511–4646) 1430 (511–4531) 1737 (642–5286) 1554 (662–5258) 3183 (938–11,250)
Payment range, $ 92–216,035 92–160,610 95–190,726 31–144,593 31–711,965
Physicians with specific payments, n (%)
Any payments 760 (47.1%) 730 (45.2%) 743 (46.0%) 724 (44.9%) −1.3 (−2.9–0.4) 0.13 1055 (65.4)
Payments > $500 612 (37.9%) 594 (36.8%) 628 (38.9%) 616 (38.2%) 0.8 (−1.1–2.6) 0.43 930 (57.6)
Payments > $1000 482 (29.9%) 436 (27.0%) 485 (30.0%) 453 (28.1%) −0.8 (−2.9%–1.3) 0.45 776 (48.1)
Payments > $5000 175 (10.8%) 178 (11.0%) 193(12.0%) 187 (11.6%) 2.8 (−0.8–6.5) 0.13 419 (26.0)
Payments > $10,000 106 (6.6%) 94 (5.8%) 113 (7.0%) 103 (6.4%) 1.0 (−3.6–5.7) 0.68 290 (18.0)
Payments > $50,000 16 (1.0%) 14 (0.9%) 17 (1.1%) 14 (0.9%) −1.9 (−15.9–14.3) 0.80 82 (5.1)
Payments > $100,000 4 (0.2%) 3 (0.2%) 1 (0.1%) 2 (0.1%) −28.3 (−52.4–8.1) 0.11 43 (2.7)
Gini index 0.878 0.881 0.870 0.876 0.860
Pharmaceutical companies with four-year payment data
Total payments, $ 4,597,653 4,205,920 4,492,988 4,314,421 17,610,982
Average payments (SD), $ 6074 (15,169) 5562 (13,383) 6105 (13,312) 5992 (12,825) −1.3 (−4.7–2.3) 0.48 16,788 (44,820)
Median payments (IQR), $ 1603 (511–4642) 1430 (511–4525) 1737 (613–5280) 1552 (662–5258) 3183 (920–11,238)
Payment range, $ 92–215,089 92–160,610 92–190,726 31–143,571 31–709,997
Physicians with specific payments, n (%)
Any payments 757 (46.9) 730 (45.3) 736 (45.6) 720 (44.6) −1.4 (−3.1–0.2) 0.093 1049 (65.0)
Payments >$500 609 (37.7) 593 (36.7) 620 (38.4) 610 (37.8) 0.5 (−1.4–2.4) 0.60 927 (57.4)
Payments > $1000 478 (29.6) 436 (27.0) 481 (29.8) 452 (28.0) −0.7 (−2.8–1.4) 0.51 768 (47.6)
Payments > $5000 172 (10.7) 179 (11.1) 191 (11.8) 186 (11.5) 3.1 (−0.6–6.8) 0.10 415 (25.7)
Payments > $10,000 106 (6.6) 94 (5.8) 112 (7.1) 103 (6.4) 0.9 (−3.7–5.6) 0.71 289 (17.9)
Payments > $50,000 14 (0.9) 14 (0.9) 17 (1.1) 14 (0.9) 0.0 (−13.7–15.9) 1.0 82 (5.1)
Payments > $100,000 4 (0.2) 3 (0.2) 1 (0.1) 2 (0.1) −28.3 (−52.4–8.1) 0.11 42 (2.6)
Gini index 0.879 0.881 0.871 0.876 0.860

IQR: interquartile range; SD: standard deviation.