Figure 1.
Escherichia coli K1 induces neutrophil recruitment into CNS of infected mice. (a,b) Neutrophil counts (a) and bacterial loads (b) in the mouse brain 4, 12, 24, and 48 h after intravenous injection with E. coli K1 or PBS. Data are presented as mean ± SD, n = 6 mice per group. (c,d) Neutrophil counts (c) and bacterial loads (d) in the Ly-6G-antibody-treated or isotype-treated (negative control) mouse brain 24 h after intravenous injection with E. coli K1. n = 6 mice per group. p values were determined using Mann–Whitney U test. * p < 0.05; ** p < 0.01.