Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 10;23(12):6501. doi: 10.3390/ijms23126501

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effects of combination treatment of sorafenib and orlistat on proliferation and apoptosis pathways in (A) Huh7 and (B) Huh7/SR cells. Combination treatment effectively suppressed pERK and Bcl-2 expressions in Huh7 cells compared to single treatments. Decreased expression resulting from combination treatment was also seen in Huh7/SR cells but less pronounced. Additionally, combination treatment enhanced the BAX/Bcl-2 ratio in both cell lines. a, compared to Control; b, compared to Sorafenib; c, compared to Orlistat; ¹ p < 0.05; ² p < 0.01; ³ p < 0.001.