Table 1.

Affinity energy comparison of dispirooxindole (a) and the previously described [27] spirooxindole-β-lactam (b).

Compound	Figure 2 Entry#	Stereoisomer	Affinity (kcal/mol)
	a1	(3R,3′S)	−10.1
	a2	(3S,3′R)	−9.1
	a3	(3R,3′R)	−8.8
	a4	(3S,3′S)	−8.1
	b1	(2R,3S)	−9.2
	b2	(2S,3R)	−9.4
	b3	(2R,3R)	−8.1
	b4	(2S,3S)	−7.3