ALK |
Anaplastic lymphoma kinase |
AML |
Acute myeloid leukemia |
BTK |
Bruton’s tyrosine kinase |
Car-DPPYs |
carbonyl-substituted diphenylpyrimidine derivatives |
DFG |
(Asp-Phe-Gly) motif |
DPPYs |
Diphenylpyrimidine analogs |
EGFR |
Endothelial growth factor receptor |
ERK |
Extracellular signal-regulated kinases |
FAK |
Focal adhesion kinase |
FAKIs |
FAK inhibitors |
FAT |
Focal Adhesion Targeting |
GBM |
Malignant glioblastoma |
Grb2 |
Growth factor receptor-bound protein 2 |
HCC |
Hepatocellular carcinoma cell |
HDAC |
histone deacetylases |
HUVEC |
Human Umbilical Vein Endothelial Cells |
IGF-IR |
Insulin-like growth factor-I receptor |
JNK |
Janus kinase |
MAPK |
Mitogen-activated protein kinase kinase |
NSCLC |
Non-small cell lung cancer |
NF-kB |
Nuclear factor-κB |
PA-DPPYs |
phosphamide-containing diphenylpyrimidine analogs |
PC |
pancreatic cells |
PDGFR |
Platelet-derived growth factor receptor |
PET |
Positron emission tomography |
PROTAC |
Proteolysis targeting chimera |
PRP |
Poly-prolin- rich sequences |
Pyk2 |
Proline-rich tyrosine kinase 2 |
ROS |
reactive oxygen species |
Sul-DPPYs |
sulphonamide-substituted diphenylpyrimidine derivatives |
TOP1 |
Topoisomerase I |
VEGFR |
Vascular endothelial growth factor receptor |
VHL |
Von Hippel-Lindau |