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C2C12 myotubes exposed to hydrogen peroxide (500 µM, 24 h) in presence or absence of tadalafil (1 µM, 30 min pre-treatment, and then combined treatments for the following 24 h) were analyzed for DHT (A) and T (B) release. Data are presented as the percentage of release vs. ctrl ± SE. * p < 0.05 and ** p < 0.01 vs. ctrl; § p < 0.05 vs. H2O2.
