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IC50 values [μM] on non-cancerous cell lines’ keratinocytes, fibroblasts and MCF10A for most active compounds of each metal class, Ni1, Pd3, Pt4, and their reference cisplatin.
| Cell Line | Ni1 [μM] | Pd3 [μM] | Pt4 [μM] | CDDP [μM] |
|---|---|---|---|---|
| Keratinocytes | 87.0 (±0) | 55.0 (±6.7) | >100 | 5.7 (±3.1) |
| Fibroblasts | 84.3 (±8.9) | 42.9 (±10.2) | >100 | 4.1 (±1.1) |
| MCF10A | 19.6 (±2.6) | 28.3 (±16.8) | 41.5 (±25.8) | 3.3 (±0.6) |
