Table 4.
Survival of the whole cohort of patients with NB in relation to FANCA gene-expression values, evaluated by the multivariable Cox regression model.
| Overall Survival | Event Free Survival | |||||
|---|---|---|---|---|---|---|
| Gene Expression | HR | 95% CI | p | HR | 95% CI | p |
| Median | 0.070 | <0.001 | ||||
| ≤3.388 (reference) | 1 | - | 1 | - | ||
| >3.388 | 1.3 | 0.98–1.8 | 1.6 | 1.3–2.1 | ||
| Tertiles | 0.054 * | <0.001 * | ||||
| ≤3.051 (reference) | 1 | - | 1 | - | ||
| 3.051–3.749 | 1.3 | 0.88–1.9 | 1.4 | 1.1–2.0 | ||
| >3.749 | 1.4 | 1.0–2.1 | 1.9 | 1.4–2.6 | ||
HR: Hazard ratio. Multivariable analysis: HRs are adjusted by MYCN status, age, and stage at diagnosis. * Test for trend.