Table 4.
Multivariate analysis of the prognostic factors of disease-free survival in patients with stage II/III gastric cancer.
| Factors | Hazard Ratio | 95% Confidence Interval | p Value | |
|---|---|---|---|---|
| Lower | Upper | |||
| Type of gastrectomy | ||||
| Total/partial | 1.149 | 1.000 | 1.319 | 0.050 |
| Tumor size (cm) | ||||
| 2.41–3.9/≤2.4 | 1.167 | 0.913 | 1.491 | 0.217 |
| 3.91–9.4/≤2.4 | 1.397 | 1.113 | 1.754 | 0.004 |
| >9.4/≤2.4 | 1.581 | 1.177 | 2.124 | 0.002 |
| Stage (AJCC eighth edition) | ||||
| IIB/IIA | 1.598 | 1.108 | 2.306 | 0.012 |
| IIIA/IIA | 1.766 | 1.232 | 2.531 | 0.002 |
| IIIB/IIA | 1.998 | 1.344 | 2.971 | <0.001 |
| IIIC/IIA | 2.283 | 1.493 | 3.492 | <0.001 |
| LN ratio | ||||
| 0.051–0.15/≤0.05 | 1.595 | 1.239 | 2.053 | <0.001 |
| 0.151–0.37/≤0.05 | 2.364 | 1.817 | 3.075 | <0.001 |
| 0.371–0.53/≤0.05 | 3.116 | 2.270 | 4.276 | <0.001 |
| >0.53/≤0.05 | 4.570 | 3.288 | 6.354 | <0.001 |
| Histological type | ||||
| Differentiated/undifferentiated | 1.029 | 0.896 | 1.182 | 0.685 |
| Vascular invasion | ||||
| Yes/no | 1.074 | 0.918 | 1.256 | 0.374 |
| Lymphatic invasion | ||||
| Yes/no | 1.161 | 0.963 | 1.400 | 0.118 |
| Perineural invasion | ||||
| Yes/no | 1.227 | 1.063 | 1.415 | 0.005 |
AJCC—American Joint Committee on Cancer; LN ratio—metastatic to examined lymph node ratio.