Table 5.
Multivariate analysis of the prognostic factors of cancer-specific survival in patients with stage II/III gastric cancer.
| Factors | Hazard Ratio |
95% Confidence Interval | p Value | |
|---|---|---|---|---|
| Lower | Upper | |||
| Type of gastrectomy | ||||
| Total/partial | 1.149 | 0.999 | 1.320 | 0.051 |
| Tumor size (cm) | ||||
| 2.41–3.9/≤2.4 | 1.189 | 0.927 | 1.525 | 0.173 |
| 3.91–9.4/2.4 | 1.439 | 1.142 | 1.813 | 0.002 |
| >9.4/≤2.4 | 1.692 | 1.254 | 2.282 | <0.001 |
| Stage (AJCC eighth edition) | ||||
| IIB/IIA | 1.558 | 1.075 | 2.259 | 0.019 |
| IIIA/IIA | 1.796 | 1.249 | 2.583 | 0.002 |
| IIIB/IIA | 2.082 | 1.396 | 3.106 | <0.001 |
| IIIC/IIA | 2.357 | 1.535 | 3.619 | <0.001 |
| LN ratio | ||||
| 0.051–0.15/≤0.05 | 1.547 | 1.201 | 1.993 | <0.001 |
| 0.151–0.37/≤0.05 | 2.249 | 1.728 | 2.928 | <0.001 |
| 0.371–0.53/≤0.05 | 2.943 | 2.145 | 4.039 | <0.001 |
| >0.53/≤0.05 | 4.331 | 3.114 | 6.024 | <0.001 |
| Histological type | ||||
| Differentiated/undifferentiated | 1.058 | 0.921 | 1.215 | 0.427 |
| Vascular invasion | ||||
| Yes/no | 1.062 | 0.906 | 1.243 | 0.459 |
| Lymphatic invasion | ||||
| Yes/no | 1.168 | 0.969 | 1.408 | 0.104 |
| Perineural invasion | ||||
| Yes/no | 1.231 | 1.066 | 1.421 | 0.005 |
AJCC—American Joint Committee on Cancer; LN ratio—metastatic to examined lymph node ratio.