Figure 5.
The effect of GO on the production of ROS in breast cancer cells. (A) Generation of ROS in MCF-7 cells induced by GO and bacteria-reduced GO (B-rGO) (treated groups showed statistically significant higher ROS production with respect to the control (*: p < 0.05)). The figure is adapted from [147], copyright 2013 Gurunathan et al., originally published by and used with permission from Dove Medical Press Ltd. (B) ROS production induced by rGO in MDA-MB-231 and ZR-75-1 cells with different concentrations of nanoparticles. The figure is adapted with open-access permission from [118], copyright 2021 Kretowski et al., publisher and licensee MDPI. (C) Oxidative stress caused by different concentrations of rGO and measured through DCFDA assay on MCF-7 and MDA-MB-231 breast cancer cells and MCF-10A normal breast cells. Figures are reprinted and adapted with permission from [119], copyright 2020 American Chemical Society.