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. 2022 Jun 4;8(6):605. doi: 10.3390/jof8060605

Table 1.

Cytotoxicity evaluation of the AgNPs biologically synthesised by the fungus C. thermophilum using the NRU assay with the skin fibroblasts from the murine embryo Balb/c 3T3 NIH cell line: IC values, the predicted LD50 (which, given all at once, could cause the death of 50% of a group of test animals) and the GHS for the AgNPs’ cytotoxic effects.

IC Predicted LD50 GHS
µg/mL mg/kg
IC80 144.92 ± 23.33 624.31 ± 41.87 4
IC50 119.69 ± 21.15
IC20 91.77 ± 24.24