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. 2022 Jun 18;23(12):6806. doi: 10.3390/ijms23126806

Figure 2.

Figure 2

The various mechanisms and factors inducing the metastasis of breast cancer. Induction of EMT is directly related to the metastasis of breast cancer. In addition, multiple cytokines secreted by TME and epigenetic modification promote breast cancer metastasis by maintaining and expanding cancer stem cells with drug resistance and metastatic potential.