Table 2.

Results of the univariate linear regression analysis. Results of the multivariate linear regression analysis regarding the determined Patient State Index and sedation dosages administered. Abbreviations: RASS, Richmond Agitation and Sedation Scale; µg, microgram; mg, milligram; kg, kilogram bodyweight; min, minute; h, hour; MAC, minima alveolar concentration; IQR, interquartile range; CI, confidence interval.

Variable	Estimate	Standard Error	p-Value	CI 95%	Mean Dosage [IQR]
propofol	8.9	0.18	<0.0001	(8.5;9.3)	3.0 [2.0] mg/kg/h
midazolam	−192.12	2.97	<0.0001	(−197.9; −186.3)	0.2 [0.1] mg/kg/min
clonidine	−32.11	0.42	<0.0001	(−32.9; −31.3)	2.0 [0.5] µg/kg/min
sufentanil	−85.74	1.59	<0.0001	(−88.9; −82.6)	0.2 [0.1] µg/kg/min
esketamine	60.09	1.54	<0.0001	(57.1; 63.1)	1.5 [1.15] mg/kg/h
RASS	12.5	0.18	<0.0001	(12.1; 12.9)