Infertility as defined by Word Health Organization standards |
American Fertility Score III/IV and pre-treatment with a gonadotrophin-releasing hormone analog |
Written, conscious consent of the patient |
No written consent given |
Age 18–45 |
Age < 18 or >45 |
Qualification and performance of the in vitro procedure |
Disqualification of the patient, and excluding her from the IVF procedure in accordance with the criteria and qualifications described in the current recommendations and guidelines |
No use of probiotic, prebiotic, or synbiotic preparations for at least 3 months before the examination, regardless of the form of administration |
Use of probiotic, prebiotic, or symbiotic preparation for at least 3 months before the examination, regardless of the form of administration |
Undergoing sample transfer procedure |
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No use of antibiotics in the period of at least 3 months before the examination, regardless of the form of administration |
Use of antibiotics in the period of at least 3 months before the examination, regardless of the form of administration |
No current or past neoplastic disease |
Current or past neoplastic disease |
No mental or emotional disorders |
Mental or emotional disorders |
Caucasian race |
Race other than Caucasian |
No malformations of the uterus and fallopian tubes |
Previous pregnancy or miscarriage in their medical history |
No vaginal infections (vaginal discharge, itching, burning, pain, bad smell) |
Current or last 3 months before study vaginal infections |
No endometriosis |
Endometriosis |
No use of hormonal contraceptives within 3 months prior to the start of their IVF intake |
Used hormonal contraceptives within 3 months prior to the start of their IVF intake |