Table 2.
Associations of cFTOE and crSaO2 with clinical characteristics of premature neonates.
| Variables | Average crStO2 | p-Value | cFTOE | p-Value |
|---|---|---|---|---|
| Sex (b) | 0.212 | 0.282 | ||
| Male | 60.54 ± 9.31 | 0.36 ± 0.10 | ||
| Female | 64.36 ± 11.61 | 0.33 ± 0.12 | ||
| Extremely premature | 0.106 | 0.138 | ||
| Gestational age < 28 weeks | 59.26 ± 9.13 | 0.37 ± 0.09 | ||
| Gestational age ≥ 28 weeks | 64.28 ± 10.99 | 0.33 ± 0.14 | ||
| Low birth weight | 0.631 | 0.756 | ||
| Birth weight < 1000 g | 61.52 ± 9.76 | 0.35 ± 0.10 | ||
| Birth weight ≥ 1000 g | 63.00 ± 11.28 | 0.34 ± 0.12 | ||
| IVH | 0.215 | 0.244 | ||
| absent | 64.92 ± 10.16 | 0.32 ± 0.11 | ||
| I–II | 59.24 ± 11.09 | 0.38 ± 0.12 | ||
| III–IV | 60.71 ± 9.05 | 0.36 ± 0.09 | ||
| Surfactant | 0.076 | 0.129 | ||
| Yes | 59.93 ± 9.37 | 0.37 ± 0.10 | ||
| No | 65.33 ± 11.28 | 0.32 ± 0.12 | ||
| Apnoea | 0.0026 * | 0.0039 * | ||
| Yes | 56.84 ± 9.83 | 0.40 ± 0.10 | ||
| No | 65.86 ± 9.45 | 0.31 ± 0.10 | ||
| Inotropic iv | <0.0001 * | <0.0001 * | ||
| Yes | 54.29 ± 7.04 | 0.42 ± 0.08 | ||
| No | 66.68 ± 9.48 | 0.30 ± 0.10 | ||
| Neonatal sepsis | 0.106 | 0.138 | ||
| Yes | 59.26 ± 9.13 | 0.37 ± 0.09 | ||
| No | 64.28 ± 10.99 | 0.33 ± 0.14 | ||
| Metabolic acidosis | 0.147 | 0.155 | ||
| No/mild (pH > 7.2) | 66.19 ± 11.33 | 0.31 ± 0.12 | ||
| Moderate (7.0 < pH < 7.2) | 60.86 ± 9.37 | 0.36 ± 0.10 | ||
| Severe (pH < 7) | 56.75 ± 12.34 | 0.41 ± 0.12 | ||
| Hypocapnia | 0.047 * | 0.043 * | ||
| Yes | 65.04 ± 9.07 | 0.32 ± 0.09 | ||
| No | 59.05 ± 11.32 | 0.38 ± 0.12 |
IVH: intraventricular haemorrhage; crSaO2: cerebral regional oxygen saturation; cFTOE: cerebral fractional tissue oxygen extraction; (b) data were expressed using descriptive statistics as mean ± standard deviation and absolute (relative) frequencies; * significant level: p < 0.05.