Table 3.
Prophylaxis regimen and FVIII consumption.
| One Year Pre-BAY 81-8973 |
One Year Post-BAY 81-8973 |
Δ (%) |
p-Value * | |
|---|---|---|---|---|
| Prophylaxis | ||||
| IU/Kg/Infusion Mean (±SD) |
30.66 (±5.03) |
31.65 (±4.96) |
+0.99 (+3.20%) |
|
| N Infusion per week, Mean (±SD) |
3.04 (±0.42) |
2.83 (±0.43) |
−0.21 (−7.00%) |
|
| Annual prophylaxis consumption per patient °, IU | 341,319.36 | 327,706.47 |
−13,612.89
(−4.00%) |
0.117 |
| Treatment of bleeds | ||||
| ABR, Mean (±SD) | 1.76 (±4.15) |
0.23 (±0.60) |
−1.53
(−87.0%) |
|
| IU/Kg/Infusion, Mean (±SD) |
36.95 (±4.15) |
36.14 (±11.54) |
−0.81 (−2.20%) |
|
| N ° of Infusion, Mean (±SD) |
3.00 (±1.84) |
3.14 (±3.53) |
0.14 (4.70%) |
|
| Annual bleeding consumption per patient °, IU | 13,746.29 | 1817.47 |
−11,928.82
(−86.70%) |
<0.001 |
| Total Consumption per patients °, IU | 355,065.65 | 329,523.94 |
−25,541.71
(−7.20%) |
0.046 |
° Estimated on average weight of 70.4 kg. * p-value estimated with paired Wilcoxon Signed-Rank Test.