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. 2022 Jun 9;12(6):947. doi: 10.3390/jpm12060947

Table 2.

Most frequently selected single feature for each tissue expression imputation model and its performance in classifying NDR vs. DR.

Tissue Expression Model Selected Feature Selection Frequency AUC-ROC (SD)
Training 5-CV Set Test Set
Whole blood DPY19L3 79/100 0.845 (0.027) 0.839 (0.070)
Colon transverse TXNDC16 40/100 0.728 (0.060) 0.711 (0.150)
Small intestine terminal ileum ENSG00000270127 14/100 0.738 (0.050) 0.720 (0.120)

5CV, five-fold cross-validation; AUC-ROC, area under the receiver operating characteristic curve; SD, standard deviation; NDR, non-durable response; DR, durable response.