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. 2022 Jun 14;11(12):3412. doi: 10.3390/jcm11123412

Table 4.

The occurrence of constipation during the probiotic treatment.

Study Duration (Days) Frequency and Character (Percentage of Patients, %) Wexner Score (Percentage of Patients, %) Gener Result 1
Study Group Control Group Study Group Control Group Study Group Control Group
ADULTS POPULATION
Chemotherapy treatment
Liu J. et al. [36] N/A N/A Markedly 2: 18
Effective 3: 78
Invalid 4: 4
Markedly: 8
Effective: 24
Invalid: 68
0–10: 37
11–20:13
21–30:0
0–10: 35
11–20: 15
21–30: 0
improvement
CHILD POPULATION
Chemotherapy treatment
Reyna-Figueroa J. et al. [38] up to 5 up to 7 N/A N/A N/A N/A improvement

1 Significantly better outcomes in the study group in at least one parameter (α = 0.05); 2 Markedly: stool returned to normal and the frequency to once a day after treatment; 3 Effective: stool character improved and the frequency became more than 3 times per week after treatment; 4 Invalid: no improvement in frequency and character of stool after treatment.