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. 2022 Jun 23;11:e72879. doi: 10.7554/eLife.72879

Figure 5. The role of USPL1 role in the Little Elongation Complex.

Figure 5.

(A) Hierarchical clustering of log2FC values of differentially expressed genes (adjusted p-value <0.05) 96 h following knockout of USPL1, ICE1, ELL, ICE2, and EAF1 in MDAMB231. (B) Gene sets significantly enriched (FDR <0.05) for the conditions shown in (A). The top five up- and down-regulated gene sets for each condition are shown.