Genetic structure of the Ecuadorian ethnic groups evaluated by pairwise FST analyses. (A) Visualization of the matrix of pairwise FST values, and (B) multidimensional scaling analysis (MDS) based on FST genetic distances calculated from the 46 AIM-INDELs. (C) Visualization of the matrix of pairwise FST values, and (D) multidimensional scaling analysis (MDS) based on FST genetic distances calculated from the genetic variants found in DPYD. The groups analyzed correspond to Afro-Ecuadorian (AFE), Mestizo (MEZ), and Indigenous (IND) ethnic groups, belonging to the Coast (CO), Andes (HG), and Amazon Region (AZ).