Figure 2.

KdmA and KdmB regulate normal growth and asexual development in different ways. (A) Colony photographs and growth of WT, ΔkdmA, and ΔkdmB strains point-inoculated on various solid media and grown in solid glucose minimal medium with 0.1% yeast extract (MMY), 10 g/L yeast extract + 30 g/L glucose (YG), or potato dextrose agar (PDA) for 3 days and determined colony diameter. (B) Conidia numbers produced by each strain per plate. (C) Transcript levels of the key asexual developmental regulators in the mutants relative to the corresponding level in the WT strain at 3 days determined by quantitative RT-PCR (RT-qPCR). Dot line indicates the level of WT transcript. Fungal cultures were grown in MMY, and mRNA levels were normalized to the expression level of the ef1α gene. Statistical significance of differences was assessed by Student’s t-test: * p < 0.05, ** p < 0.01.