Table 2.
Summary of the groups identified by the integration of a DE analysis and an interaction network built with the proteomics data.
| GO group | Marker | CAS changes |
|---|---|---|
| G1 (CW organization) |
Pga52 | Msb2, C3_07470W_A |
| G2 (Germ-tube formation) |
Gsc1 (Fks1), C2_04780W_A | Slr1 |
| G3 (Modulation of host response) |
Pga10, Rbt5 | Pga31, Skn1 |
| G4 (Adhesion to the host) |
Sap10*, Als1* | Als3* |
| G5 (Ribosomal proteins) |
Rhd3 | Sim1 |
| G6 (Glucose transporters) |
Hgt7,8 | |
| G0 (Ungrouped proteins) |
Plb5 | Cht2, Sik1, Phr1, Rpa34, Tos1 |
The marker column indicates the proteins for each group that were significant for the DE analysis and the CAS changes column the proteins changing in presence of caspofungin for both drug-resistant and –susceptible isolates. *not significant.