Table 5.

Adjusted health care costs by time from HZ index date and by payer

Opioid HZ cohort vs non-opioid HZ cohorts
	Overall			Commercial			Medicare			Medicaid
Time period after the index date	Opioid HZ cohort	Non-opioid HZ cohort	Difference	Opioid HZ cohort	Non-opioid HZ cohort	Difference	Opioid HZ cohort	Non-opioid HZ cohort	Difference	Opioid HZ cohort	Non-opioid HZ cohort	Difference
Month 1	$2,545	$1,317	$1,228	$2,663	$1,375	$1,288	$3,285	$1,822	$1,463	$1,383	$1,107	$276
Month 2	$2,208	$1,104	$1,104	$2,443	$1,204	$1,239	$2,478	$1,473	$1,005	$1,392	$1,227	$165
Month 3	$2,235	$1,078	$1,157	$2,464	$1,183	$1,281	$2,692	$1,477	$1,215	$1,894	$1,467	$427
Quarter 1	$6,081	$2,845	$3,236	$6,759	$3,136	$3,623	$7,815	$4,294	$3,521	$4,145	$3,214	$931
Quarter 2	$5,899	$2,667	$3,232	$6,134	$2,748	$3,386	$6,823	$3,713	$3,110	$4,439	$3,192	$1,247
Year 1	$23,599	$9,937	$13,662	$25,389	$10,650	$14,739	$27,862	$15,699	$12,163	$20,048	$13,730	$6,318

Opioid HZ cohort vs matched non-HZ cohort
	Overall			Commercial			Medicare			Medicaid
Time period after the index date	Opioid HZ cohort—matched	Matched non-HZ cohort	Difference	Opioid HZ cohort—matched	Matched non-HZ cohort	Difference	Opioid HZ cohort—matched	Matched non-HZ cohort	Difference	Opioid HZ cohort—matched	Matched non-HZ cohort	Difference
Month 1	$2,329	$1,118	$1,211	$2,298	$1,287	$1,011	$3,048	$1,645	$1,403	$1,378	$1,023	$355
Month 2	$2,178	$1,028	$1,150	$2,381	$1,029	$1,352	$2,356	$1,389	$967	$1,287	$1,185	$102
Month 3	$2,089	$987	$1,102	$2,310	$1,018	$1,292	$2,519	$1,369	$1,150	$1,890	$1,329	$561
Quarter 1	$5,812	$2,516	$3,296	$6,429	$2,891	$3,538	$7,618	$4,109	$3,509	$4,099	$3,105	$994
Quarter 2	$5,690	$2,128	$3,562	$5,981	$2,579	$3,402	$6,694	$3,683	$3,011	$4,328	$3,078	$1,250
Year 1	$21,892	$9,104	$12,788	$24,971	$9,872	$15,099	$26,955	$15,088	$11,867	$19,873	$13,029	$6,844

HZ: herpes zoster.