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. 2022 Jun 9;9(6):187. doi: 10.3390/jcdd9060187

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© 2022 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Morphogenesis of the human embryonic heart tube during Carnegie-stage 10. (A,B) depict early and late linear heart tube stages; (C) depicts a heart tube at the onset of cardiac looping; and (D) depicts a C-shaped heart tube. Hearts are shown in ventral views. The longitudinal white line indicates the original ventral midline of the heart tube. The shape of the endocardial lumen can be seen through the semitransparent wall of the hearts. It is indicated by red (ventricles, outflow tract, arteries) and blue (veins, atria, atrioventricular canal) colors. Drawings are based on Figures 18–24 shown in reference [10]. Abbreviations: AVC = atrioventricular canal; LA = embryonic left atrium; LV = embryonic left ventricle; RA = embryonic right atrium; RV = embryonic right ventricle.