Table 1.
Summary of Mean±Standard Error of the Mean and Statistics for Listed Measurements
| Test | Age | Ctrl | THC | CBD | THC+CBD | F (one-way ANOVA) | p |
|---|---|---|---|---|---|---|---|
| Male body weight (g) | P21 | 15.33±0.36 (n=63) | 14.15±0.41 (n=35) | 15.46±0.54 (n=34) | 14.52±0.39 (n=26) | F (3, 154)=2.029 | 0.1122 |
| Female body weight (g) | P21 | 14.11±0.39 (n=57) | 14.37±0.35 (n=24) | 15.24±0.43 (n=34) | 14.62±0.42 (n=31) | F (3, 142)=1.455 | 0.2295 |
| Male body weight (g) | P60–70 | 39.59±0.56 (n=55) | 39.10±0.46 (n=56) | 40.59±0.45 (n=56) | 40.93±0.72 (n=38) | F (3, 201)=2.468 | 0.0633 |
| Female body weight (g) | P60–70 | 32.89±0.58 (n=65) | 31.03±0.45 (n=53) | 32.84±0.60 (n=57) | 32.31±0.55 (n=45) | F (3, 216)=2.454 | 0.0642 |
| Male OFA 10 min (m) | P80–90 | 37.92±1.82 (n=31) | 36.15±1.64 (n=29) | 39.00±1.9 (n=17) | 39.67±1.79 (n=21) | F (3, 94)=0.7228 | 0.5408 |
| Female OFA 10 min (m) | P80–90 | 34.12±1.7 (n=29) | 36.63±1.42 (n=26) | 38.01±1.57 (n=26) | 36.16±1.46 (n=26) | F (3, 103)=1.105 | 0.3508 |
| Male SPT (%) | P90–100 | 75.95±1.90 (n=21) | 78.90±2.36 (n=11) | 85.55±2.74 (n=7)* | 86.98±1.73 (n=11)* | F (3, 46)=6.044 | 0.0015 |
| Female SPT (%) | P90–100 | 82.32±1.88 (n=20) | 88.56±2.35 (n=10) | 80.99±4.34 (n=10) | 81.16±3.28 (n=10) | F (3, 46)=1.338 | 0.2737 |
| Male marbles buried (%) | P90–100 | 77.14±3.23 (n=21) | 77.09±4.80 (n=11) | 76.14±7.37 (n=7) | 80.09±3.33 (n=11) | F (3, 46)=0.1329 | 0.9400 |
| Female marbles buried (%) | P90–100 | 76.90±2.12 (n=20) | 92.60±2.72 (n=10)* | 88.00±3.22 (n=10)* | 78.00±3.15 (n=10) | F (3, 46)=7.846 | 0.0002 |
| Male nestlet shredding (%) | P90–100 | 66.33±5.58 (n=21) | 80.42±4.43 (n=11) | 69.43±8.52 (n=7) | 82.60±4.46 (n=11) | F (3, 46)=1.970 | 0.1317 |
| Female nestlet shredding (%) | P90–100 | 73.21±5.71 (n=19) | 65.50±7.23 (n=10) | 78.40±6.52 (n=10) | 75.70±6.77 (n=10) | F (3, 45)=0.5836 | 0.6289 |
Ctrl group includes adult progenies from both naive and vehicle-treated dams. n, animal number. Statistical analyses were conducted with one-way ANOVA followed by the Bonferroni post hoc test.
*
Significant difference from ctrl.
ANOVA, analysis of variance; CBD, cannabidiol; OFA, open field arena; P21, postnatal day 21; SPT, sucrose preference test; THC, Δ9-tetrahydrocannabinol.