Table 2.

Alpha diversity in healthy controls and anti-Ro positive mothers

Taxonomic Level	Healthy Controls (N = 23) H (eH)	Asym/UAS*(N = 43) H (eH)	SS/SLE (N = 82) H (eH)	P-value1 Healthy Controls vs. All RRNL	P-value2 Healthy Controls vs. Asym/UAS vs. SS/SLE	P-value1 Asym/UAS vs. SS/SLE
Phylum	0.68 ± 0.25(1.98)	0.80 ± 0.21(2.22)	0.76 ± 0.22(2.14)	0.0195	0.065	0.9466
Class	1.11 ± 0.30(3.02)	1.05 ± 0.22(2.86)	1.06 ± 0.24(2.89)	0.4127	0.477	0.334
Order	1.11 ± 0.31(3.05)	1.06 ± 0.22(2.88)	1.07 ± 0.24(2.92)	0.3832	0.4601	0.3404
Family	1.74 ± 0.31(5.70)	1.80 ± 0.24(6.03)	1.69 ± 0.29(5.44)	0.991	0.3422	0.1414
Genus	2.77 ± 0.36(16.02)	2.74 ± 0.44(15.51)	2.62 ± 0.53(13.76)	0.1975	0.0593	0.0381
Species	2.50 ± 0.52(12.17)	2.53 ± 0.43(12.49)	2.36 ± 0.43(10.56)	0.1457	0.0045	0.0029

Results reported: mean ± standard deviation of the Shannon entropy-based diversity index (H) and the corresponding effective number of elements e^H.

*Asym/UAS represents asymptomatic and undifferentiated autoimmune syndrome (UAS) anti-Ro positive mothers of children with CHB.

¹P-value for two group comparison using a t-test.

²P-value for three group using analysis of variance with ordinal alternative reflecting clinical severity.