Table 5.
Stool taxa meeting statistical significance (FDR-adjusted P-value < 0.05) using the Taxonomic Stepdown (TSD) Method*
| |
Ordinal Test |
P-values for pairwise comparisons |
Relative abundance: Mean ± (Standard deviation) |
||||
|---|---|---|---|---|---|---|---|
| Family Genus Species | TSDPFDR | Asym/UAS vs. SS/SLE | Healthy Control vs. Asym/UAS | Healthy Control vs. SS/SLE | Healthy Controls | Asym/UAS | SS/SLE |
| Bifidobacteriaceae | 1.17E-05 | 0.4555 | 8.34E-09 | 1.09E-08 | 0.0937 ± 0.0943 | 0.0233 ± 0.0494 | 0.0308 ± 0.0545 |
| Bifidobacterium | 4.00E-05 | 0.4506 | 8.20E-09 | 1.11E-08 | 0.0997 ± 0.0998 | 0.0261 ± 0.0559 | 0.0335 ± 0.0596 |
| Actinomycetaceae | 1.68E-03 | 0.4469 | 0.0086 | 0.0006 | 0.0010 ± 0.0020 | 0.0005 ± 0.0010 | 0.0005 ± 0.0008 |
| Actinomyces | 3.24E-03 | 0.4251 | 0.0094 | 0.0006 | 0.0011 ± 0.0021 | 0.0006 ± 0.0011 | 0.0006 ± 0.0009 |
| odontolyticus | 5.00E-03 | 0.5490 | 0.0050 | 0.0005 | 0.0026 ± 0.0047 | 0.0016 ± 0.0035 | 0.0014 ± 0.0025 |
| Bacteroidaceae | 7.00E-06 | 0.6853 | 2.45E-07 | 5.12E-09 | 0.0641 ± 0.0932 | 0.1862 ± 0.1554 | 0.2149 ± 0.2102 |
| Bacteroides | 7.38E-07 | 0.6853 | 2.45E-07 | 5.12E-09 | 0.0682 ± 0.0968 | 0.1976 ± 0.1600 | 0.2265 ± 0.2169 |
| vulgatus | 4.34E-03 | 0.4218 | 6.16E-07 | 1.38E-06 | 0.0269 ± 0.0388 | 0.1335 ± 0.1343 | 0.1356 ± 0.1723 |
*TSD method started at phylum level. Means and standard deviations presented in the table are not CLR-transformed.