Scheme 1.
Reagents and conditions. (a) Et3N, DCM, 0 °C, 4 h; (b) SOCl2, reflux, 3 h; (c) EtOOC-CN, SnCl4, o-DCB, 140 °C, 15 min; (d) NaOH, EtOH, reflux, 2 h.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.