Table 2.
In vitro kinase inhibitory assay (inhibition %) of free carboxylic acid-based derivatives (6a–e) over Aurora A kinase.
| Compound | Aurora A (Inhibition%) |
|---|---|
| 6a | 7.64 ± 1.19 |
| 6b | 28.48 ± 2.40 |
| 6c | 14.83 ± 0.14 |
| 6d | 22.18 ± 1.86 |
| 6e | 51.78 ± 0.38 |
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