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In vitro kinase inhibitory assay (activity%) of compound 6e over kinase panel.
| Kinase | Compound 6e (Activity%) | Kinase | Compound 6e (Activity%) |
|---|---|---|---|
| ABL-1 | 106.77 | CDK-2/cyclin A | 83.72 |
| AKT-1 | 104.50 | CDK-8/cyclin C | 97.81 |
| ALK | 99.86 | BRAFV599E | 100.92 |
| Aurora A | 48.22 | RAF-1 | 111.64 |
| Aurora B | 92.90 | MAPK APK-2 | 99.55 |
| CAMKK-2 | 83.66 | MEK-1 | 85.42 |
| VRK-2 | 118.72 | mTOR/FRAP-1 | 105.00 |
