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. 2022 Jun 20;11(12):3544. doi: 10.3390/jcm11123544

Table 4.

Effectiveness of HDDT rescue treatment with and without bismuth.

ITT n/N (%) p * PP n/N (%) p * mITT n/N (%) p *
With B 4/13 (30.8%) 0.344 4/12 (33.3%) 0.286 4/13 (30.8%) 0.212
Without B 13/28 (46.4%) 13/25 (52%) 13/25 (52%)

B, bismuth; HDDT, high-dose dual therapy; ITT, intention to treat; mITT, modified intention to treat; n: number of patients with H. pylori infection cured; N, number of patients treated; PP, per protocol. * Adding bismuth to HDDT showed no statistically significant association with a higher eradication rate in the rescue treatment. The Chi-square test was used at a significance level of p < 0.005.