Skip to main content
. 2022 May 25;9(6):168. doi: 10.3390/jcdd9060168

Table 1.

Detailed bone structural parameters.

Parameter Control
n = 4		 Week 5
n = 4		 Week 10
n = 4		 Week 15
n = 4
Distal femur
Epiphyseal Trabecular Bone
BV/TV (%) 16.22 ± 0.37 39.3 ± 0.96 32.4 ± 0.5 27.48 ± 0.76
Tb.N (mm−1) 7.63 ± 1.11 12.86 ± 0.11 12.82 ± 0.32 12.05 ± 0.34
Tb.Th (mm) 0.052 ± 0.001 0.062 ± 0.001 0.053 ± 0.001 0.053 ± 0.001
Tb.Sp (mm) 0.59 ± 0.06 0.41 ± 0.02 0.42 ± 0.02 0.43 ± 0.02
BS/BV (mm2/mm3) 0.065 ± 0.002 0.059 ± 0.003 0.057 ± 0.003 0.062 ± 0.003
EF 0.017 ± 0.003 0.033 ± 0.005 0.034 ± 0.009 0.016 ± 0.003
EFmax 0.885 ± 0.004 0.902 ± 0.005 0.887 ± 0.004 0.88 ± 0.009
EFmin −0.82 ± 0.003 −0.825 ± 0.008 −0.812 ± 0.007 −0.81 ± 0.009
DA 1.43 ± 0.05 1.39 ± 0.04 1.42 ± 0.03 1.4 ± 0.07
Metaphyseal Trabecular Bone
BV/TV (%) 4.82 ± 0.29 24.8 ± 0.5 16.8 ± 0.75 11.86 ± 0.5
Tb.N (mm−1) 4.1 ± 0.3 13.1 ± 0.09 11.02 ± 0.07 7.62 ± 0.49
Tb.Th (mm) 0.036 ± 0.001 0.041 ± 0.001 0.037 ± 0.001 0.038 ± 0.001
Tb.Sp (mm) 0.56 ± 0.094 0.29 ± 0.04 0.27 ± 0.015 0.44 ± 0.022
BS/BV (mm2/mm3) 0.092 ± 0.003 0.085 ± 0.001 0.092 ± 0.003 0.092 ± 0.01
EF 0.12 ± 0.02 0.07 ± 0.005 0.086 ± 0.017 0.07 ± 0.03
EFmax 0.835 ± 0.019 0.87 ± 0.002 0.86 ± 0.012 0.855 ± 0.03
EFmin −0.67 ± 0.036 −0.765 ± 0.013 −0.71 ± 0.022 −0.73 ± 0.05
DA 1.77 ± 0.14 1.6 ± 0.15 1.522 ± 0.09 1.78 ± 0.09
Femoral midshaft
Cortical Bone
Mean Ct.Th (mm) 0.133 ± 0.002 0.187 ± 0.004 0.159 ± 0.001 0.137 ± 0.005
BV/TV (%) 13.9 ± 0.48 23.9 ± 0.25 20.2 ± 0.6 17.3 ± 0.24
Ps.Pm (mm) 5.65 ± 0.11 5.37 ± 0.2 5.35 ± 0.22 5.33 ± 0.18
Ec.Pm (mm) 4.75 ± 0.11 4.2 ± 0.18 4.15 ± 0.2 4.17 ± 0.21
J (mm4) 0.49 ± 0.03 0.455 ± 0.04 0.417 ± 0.007 0.5 ± 0.1

Data were a combination of males and females and collected using X-ray computed tomography of the distal femur and femoral midshaft. Values represent the mean ± SEM. BV/TV = bone volume/total volume; Tb.N = trabecular number; Tb.Th = trabecular thickness; Tb.Sp = trabecular separation; BS/BV = specific bone surface: bone surface area/bone volume; EF = ellipsoidal factor; DA = degree of anisotropy; Ct.Th = cortical thickness; Ps.Pm = periosteal perimeter; Ec.Pm = endocortical perimeter; J = polar moment of inertia.